NFL’s Week 5 slate gets underway with a matchup of NFC West rivals when the San Francisco 49ers visit the Los Angeles Rams on “Thursday Night Football.”
There will be an early Sunday football again this week as Dillon Gabriel makes his NFL debut in London, England for the Cleveland Browns as they face the Minnesota Vikings, playing the second leg of their two-game European road trip.
Lines have moved for Denver Broncos at Philadelphia Eagles, as well as for Houston Texans at Baltimore Ravens, though the latter can be attributed to expectations that Cooper Rush will be starting for the Ravens due to Lamar Jackson’s injury.
Sunday night features another division rivalry when the Buffalo Bills host the New England Patriots.
The week wraps up with the Kansas City Chiefs hitting the road to take on the Jacksonville Jaguars on “Monday Night Football” (8:15 p.m. ET on ABC/ESPN).
Bye weeks also begin, with the Atlanta Falcons, Chicago Bears, Green Bay Packers and Pittsburgh Steelers all off this weekend.
Jump to: SF-LAR | MIN-CLE | LV-IND | DAL-NYJ DEN-PHI | MIA-CAR | HOU-BAL | NYG-NO TEN-ARI | TB-SEA | WSH-LAC | DET-CIN NE-BUF | KC-JAX
Money Line: 49ers (+240); Rams (-290) Total: 46.5; Opened: 46.5 FPI favorite: Rams by 2.5 with a 56.4% probability to win the game outright
Money Line: Vikings (-195); Browns (+165) Total: 35.5; Opened: 37.5 FPI favorite: Vikings by 5.6 with a 63.87% probability to win the game outright
Money Line: Raiders (+250); Colts (-300) Total: 47.5; Opened: 48.5 FPI favorite: Colts by 5.1 with a 62.2% probability to win the game outright
Money Line: Cowboys (-140); Jets (+120) Total: 47.5; Opened: 44.5 FPI favorite: Cowboys by 3.5 with a 58.8% probability to win the game outright
Money Line: Broncos (+160); Eagles (-190) Total: 43.5; Opened: 44.5 FPI favorite: Eagles by 4.3 with a 61.53% probability to win the game outright
Money Line: Dolphins (-115); Panthers (-105) Total: 44.5; Opened: 44.5 FPI favorite: Panthers by 0.6 with a 51.2% probability to win the game outright
Money Line: Texans (-130); Ravens (+110) Total: 39.5; Opened: 43.5 FPI favorite: Ravens by 2.4 with a 56.52% probability to win the game outright
Money Line: Giants (+110); Saints (-130) Total: 40.5; Opened: 42.5 FPI favorite: Saints by 1.6 with a 54.4% probability to win the game outright
Money Line: Titans (+340); Cardinals (-450) Total: 41.5; Opened: 42.5 FPI favorite: Cardinals by 9.6 with a 73.73% probability to win the game outright
Money Line: Buccaneers (+160); Seahawks (-190) Total: 44.5; Opened: 44.5 FPI favorite: Seahawks by 1.4 with a 53.33% probability to win the game outright
Money Line: Commanders (+135); Chargers (-155) Total: 47.5; Opened: 49.5 FPI favorite: Chargers by 3.7 with a 59.53% probability to win the game outright
Money Line: Lions (-650); Bengals (+425) Total: 49.5; Opened: 48.5 FPI favorite: Lions by 11 with a 76.4% probability to win the game outright
Money Line: Patriots (+320); Bills (-425) Total: 49.5; Opened: 49.5 FPI favorite: Bills by 7.2 with a 68% probability to win the game outright
Money Line: Chiefs (-190); Jaguars (+160) Total: 46.5; Opened: 45.5 FPI favorite: Chiefs by 5 with a 62.67% probability to win the game outright
Odds as of publication time. For the most current odds, visit ESPN BET.
San Francisco 49ers vs. Los Angeles Rams -6.5 Thursday, 8:15 p.m., Prime Video
Minnesota Vikings -3.5 vs. Cleveland Browns Sunday, 9:30 a.m., NFL Net, NFL+
Las Vegas Raiders vs. Indianapolis Colts -6.5 Sunday, 1 p.m., FOX
Dallas Cowboys -2.5 vs. New York Jets Sunday, 1 p.m., FOX
Denver Broncos vs. Philadelphia Eagles -3.5 Sunday, 1 p.m., CBS
Miami Dolphins -1.5 vs. Carolina Panthers Sunday, 1 p.m., FOX
Houston Texans -1.5 vs. Baltimore Ravens Sunday, 1 p.m., CBS, CBS
New York Giants vs. New Orleans Saints -1.5 Sunday, 1 p.m., CBS
Tennessee Titans vs. Arizona Cardinals -7.5 Sunday, 4:05 p.m., CBS
Tampa Bay Buccaneers vs. Seattle Seahawks -3.5 Sunday, 4:05 p.m., CBS
Washington Commanders vs. Los Angeles Chargers -2.5 Sunday, 4:25 p.m., FOX
Detroit Lions -10.5 vs. Cincinnati Bengals Sunday, 4:25 p.m., FOX
New England Patriots vs. Buffalo Bills -7.5 Sunday, 8:20 p.m., NBC
Kansas City Chiefs -3.5 vs. Jacksonville Jaguars Monday, 8:15 p.m., ABC, ESPN