Bill ConnellyOct 3, 2025, 07:30 AM ETCloseBill Connelly is a writer for ESPN. He covers college football, soccer and tennis. He has been at ESPN since 2019.Follow on X
play0:52Vanderbilt fans storm field after historic win over AlabamaVanderbilt hangs on for its first-ever win over a No. 1 ranked team in a thrilling 40-35 victory over Alabama.
Deciphering the possibility of No. 16 Vandy taking down No. 10 Bama (1:33)Gene Chizik and Alyssa Lang debate on whether the Commodores can repeat last year’s success against the Crimson Tide and detail the elite QB matchup of Diego Pavia vs. Ty Simpson. (1:33)
Vanderbilt fans storm field after historic win over AlabamaVanderbilt hangs on for its first-ever win over a No. 1 ranked team in a thrilling 40-35 victory over Alabama.
Vanderbilt hangs on for its first-ever win over a No. 1 ranked team in a thrilling 40-35 victory over Alabama.
Welcome to October. It’s hard to see where this season is taking us, but that makes the journey awfully fun. Here’s everything you need to follow in a surprising, mysterious Week 6.
Part of succeeding a legend is that we notice anytime you don’t live up to the legend’s standards. Granted, Kalen DeBoer has proven adept at continuing Nick Saban’s relative success against Kirby Smart’s Georgia, but DeBoer’s track record otherwise has some holes. He has already lost four games to unranked teams, as many as Saban lost in 17 years. Not great.
Vanderbilt fans storm field after historic win over Alabama
The Commodores’ defense isn’t amazing, but it’s also better than it was last season. Vandy plays decent run defense with great big-play prevention against the pass; safety CJ Heard is excellent, and linebackers Bryan Longwell and Khordae Sydnor swarm well.
Alabama remains an unfinished picture. The Crimson Tide’s defense looked downright unprepared in Week 1 against Florida State, but it has allowed only 11.7 points per game since. The Crimson Tide don’t create nearly enough negative plays, but they don’t give up big plays either, and safety Bray Hubbard keys a frustrating zone defense.
The offense has been the star of the show. Ty Simpson looked disheveled against Florida State, but he has been brilliant since, and the Tide are up to sixth in points per drive despite a below-average run game. They couldn’t quite close out Georgia after a brilliant first half, but Simpson is incredibly sharp, and the offensive line has shored up a lot of its Week 1 breakdowns.
Virginia’s upset of Florida State last week damaged the hype value of one ACC matchup but heightened another. FSU hosts unbeaten Miami on Saturday evening in desperate need of a turnaround win, but the winner of the afternoon’s Virginia-Louisville game — a matchup of the teams with the second- (Louisville) and fourth-best (Virginia) ACC title odds, per SP+ — will be positioned wonderfully, too.
Even in the playoff era, though, a “stuff happens” loss can wipe out your margin for error. Thanks to early-season collapses from Clemson and Florida, Miami is the last SP+ top-40 opponent on FSU’s schedule, meaning this is likely the Seminoles’ last chance at another high-visibility win.
Considering Miami took down Florida in part due to physical running, whoever generates more success in this regard could have a huge advantage.
With tackle Rueben Bain Jr. at full force and getting help from disruptors such as linebacker Mohamed Toure and nickel back Keionte Scott, Miami’s defense might be even better than Bama’s. It will land some shots, but if FSU can hold Beck and the Canes to 24 or fewer points, you have to like the Seminoles’ chances.
Brown and Watson should be as close to full speed Saturday as they’ve been all year, and that’s good because Louisville has played against two SP+ top-50 defenses and averaged just 4.8 yards per play against them. The defense has improved a bit after slippage in recent years, thanks mostly to a pass rush led by star transfers Clev Lubin and Wesley Bailey, but for the Cardinals to live up to growing expectations, the run game will need to shift into gear.
Virginia, meanwhile, has already exceeded expectations. Obliterated them. Blown them to smithereens.
Current line: Louisville -6.5 | SP+ projection: Louisville by 9.2 | FPI projection: Louisville by 1.4
But the conference had all sorts of surprises in store. Utah lost seven games in a row, and Kansas State lost three of four down the stretch. Arizona and OSU went a combined 1-14 the rest of the way, while Arizona State transformed into a top-10 caliber team in November and won the conference title.
Texas Tech has been genuinely awesome this season, walloping three bad teams as an elite team should and then physically manhandling Utah in Salt Lake City two weeks ago. They’ve been awesome at pretty much everything — they’re fifth in yards per play on offense and defense — and aside from a predilection for penalties and some injury-prone tendencies for quarterback Behren Morton, we don’t really know their weaknesses yet.
Houston’s a little bit easier to figure out. Defense: good. Offense: not so much. The Cougars are ninth in yards per play allowed and are very much in the best quadrant of this chart.
Willie Fritz lost defensive coordinator Shiel Wood to Tech, but the UH defense has been even better with replacement Austin Armstrong. But the Conner Weigman-led offense remains a work in progress. The Coogs go three-and-out nearly 39% of the time (124th), and that will probably be their downfall in this one. But if the defense sets up some easy scoring opportunities, this one quickly moves into “upset watch” territory.
Current line: Tech -10.5 (down from -12.5 on Sunday) | SP+ projection: Tech by 13.9 | FPI projection: Tech by 7.0
Iowa State is not a track meet team. The Cyclones have allowed more than 16 points just once in five games, but they’ve also topped 24 only twice. ISU runs a lot on first down but doesn’t get very far, so quarterback Rocco Becht has to convert a lot of third downs. He usually pulls it off, though, either with deep shots to Brett Eskildsen and Chase Sowell or passes to any of four tight ends.
The ISU defense is strong once again. The Cyclones rarely invade the backfield, but Domonique Orange occupies space up front (he’s listed as probable this week), and they tackle well, prevent big plays and pounce on mistakes. Sorsby hasn’t made many mistakes lately, though.
Kansas State suffered a three-week funk after losing to Iowa State in Dublin, Ireland, but quarterback Avery Johnson just enjoyed, by far, his best game of the season, and RB Dylan Edwards is finally healthy. The Wildcats still have only one conference loss, but their next four games — at Baylor, TCU, at Kansas, Texas Tech — will require a sustained A-game. Sawyer Robertson and the prolific Bears also have one conference loss and could easily stay in the conversation with a strong performance.
UCF makes a lot of big plays but can’t keep a quarterback healthy and missed a solid upset opportunity with a poor performance at Kansas State last week. With last week’s defeat to Cincinnati, meanwhile, Kansas has dropped eight of its past nine one-score finishes since late 2023. Iowa State weathered a similar streak recently before flipping that script, and if KU does the same, it’s not too late to get into the race. It’s now or never, though.
Last week was great and terrible for Notre Dame. On one hand, the Fighting Irish looked spectacular in making Arkansas quit in a 56-13 road blowout. The offense is improving rapidly, and CJ Carr is quickly becoming one of the nation’s best quarterbacks. Meanwhile, despite injuries to star corner Leonard Moore and tackle Donovan Hinish, among others, the defense finally showed some life after a poor start to 2025. Notre Dame is the projected favorite in every remaining game.
On the other hand, the Irish’s potential CFP résumé, should they win out and get to 10-2, took a hit. USC’s loss to Illinois hurt their potential for a top-10 win, and four other upcoming opponents all lost. It will be difficult for the Irish to stand out in a pile of two-loss teams, even if they deliver blowouts.
Current line: Irish -20.5 (up from -17.5) | SP+ projection: Irish by 13.5 | FPI projection: Irish by 18.8
We’re once again using this space to will chaos into existence, looking at four carefully curated games with pretty big point spreads and mashing them together into a much more upset-friendly number. Houston’s overtime win over Oregon State cost us a fourth win in five tries — how could you do that to us, Coogs? — but 3-for-5 is still pretty good.
Going 4-for-6 is even better, though. SP+ tells us there’s only a 55% chance that Nebraska (81% win probability against Michigan State), Illinois (85% over Purdue), Michigan (88% over Wisconsin) and Ohio State (90% over Minnesota) all win. It’s time to take down a Big Ten favorite.
Here are some more games you should pay attention to if you want to get the absolute most out of the weekend, from both information and entertainment perspectives.
West Virginia at No. 23 BYU (10:30 p.m., ESPN). I’m sticking this one in the Playlist instead of the Big 12 section above because of the larger point spread. BYU overcame a poor performance to remain unbeaten against Colorado, and the Cougars could probably withstand another iffy game this weekend. But it feels like a race to get quarterback Bear Bachmeier — 48th in Total QBR, 51st in yards per dropback — ready for an epic run of high-stakes Big 12 games on the horizon.
New Mexico at San José State (10 p.m., FS1). I’m not sure anyone in college football is having more fun than New Mexico.
The Lobos frustrated Michigan, stomped UCLA and beat rival New Mexico State for the Chile Roaster trophy. Now, with trips to San José and Boise in the next two weeks, we find out if this is a fun bowl push or a fun Mountain West title push.
Clemson at North Carolina (noon, ESPN). One of the most noteworthy ACC games in the preseason — Dabo Swinney’s top-five Clemson versus Bill Belichick’s North Carolina! — still packs intrigue, but it’s mostly negative. Clemson has lost to all three of its power-conference opponents, and UNC has lost to two by a combined 82-23. Clemson likely has too much talent for the Heels, but, well, that hasn’t stopped the Tigers from playing like they have thus far.