play1:01Why Will Compton is backing Drake Maye for NFL MVPWill Compton explains why he believes Drake Maye will be named MVP and why his stats stack up with Aaron Rodgers’, Tom Brady’s and Peyton Manning’s.
play2:00Why Field Yates sees Jaxson Dart as a top fantasy QB in Week 10Field Yates explains why Jaxson Dart has one of the highest fantasy quarterback outlooks in Week 10 against the Bears.
play0:45What does Kyler Murray on IR mean for Cardinals?Adam Schefter reports on Jacoby Brissett being named the Cardinals’ starting quarterback with Kyler Murray placed on injured reserve.
play0:42Calvin Johnson to McAfee: Matthew Stafford makes it look so easyCalvin Johnson tells Pat McAfee how his former Lions teammate Matthew Stafford’s game has improved since joining the Rams.
play0:48Orlovsky: Joe Alt injury enormous loss for ChargersDan Orlovsky breaks down why offensive tackle Joe Alt’s injury could be a season-changing loss for the Chargers.
Are the Jets taking the right approach to rebuild? (2:26)Kimberley Martin defends the Jets’ approach in trading away Quinnen Williams and Sauce Gardner in a debate with Louis Riddick and Mike Greenberg. (2:26)
Why Will Compton is backing Drake Maye for NFL MVPWill Compton explains why he believes Drake Maye will be named MVP and why his stats stack up with Aaron Rodgers’, Tom Brady’s and Peyton Manning’s.
Will Compton explains why he believes Drake Maye will be named MVP and why his stats stack up with Aaron Rodgers’, Tom Brady’s and Peyton Manning’s.
Why Field Yates sees Jaxson Dart as a top fantasy QB in Week 10Field Yates explains why Jaxson Dart has one of the highest fantasy quarterback outlooks in Week 10 against the Bears.
Field Yates explains why Jaxson Dart has one of the highest fantasy quarterback outlooks in Week 10 against the Bears.
What does Kyler Murray on IR mean for Cardinals?Adam Schefter reports on Jacoby Brissett being named the Cardinals’ starting quarterback with Kyler Murray placed on injured reserve.
Adam Schefter reports on Jacoby Brissett being named the Cardinals’ starting quarterback with Kyler Murray placed on injured reserve.
Calvin Johnson to McAfee: Matthew Stafford makes it look so easyCalvin Johnson tells Pat McAfee how his former Lions teammate Matthew Stafford’s game has improved since joining the Rams.
Calvin Johnson tells Pat McAfee how his former Lions teammate Matthew Stafford’s game has improved since joining the Rams.
Orlovsky: Joe Alt injury enormous loss for ChargersDan Orlovsky breaks down why offensive tackle Joe Alt’s injury could be a season-changing loss for the Chargers.
Dan Orlovsky breaks down why offensive tackle Joe Alt’s injury could be a season-changing loss for the Chargers.
(American) football will be played in Germany between the Falcons and Colts. Back in the States, Drake Maye and Baker Mayfield will face off in what’s expected to be an intriguing QB duel, and Detroit will seek revenge against the Commanders after losing to them in the 2024 playoffs.
Let’s get into the full Week 10 slate, which culminates with a “Monday Night Football” matchup between the Eagles and Packers on ESPN. (Game times are Sunday unless otherwise noted.)
Jump to a matchup: ATL-IND | BAL-MIN | NE-TB BUF-MIA | JAX-HOU | NYG-CHI NO-CAR | CLE-NYJ | LAR-SF DET-WSH | ARI-SEA | PIT-LAC PHI-GB
What we’re hearing on the Falcons: Atlanta’s defense has been mostly good this season, allowing the fourth-fewest yards per game in the league (282.5). But it has been vulnerable on the ground, ranked just 26th in expected points added per designed run (minus-0.03). On Sunday in Berlin, the Falcons have to contend with Jonathan Taylor, one of the NFL’s best running backs, whom coach Raheem Morris referred to as someone “you need to bring a lot of people to tackle.” — Marc Raimondi
Stat to know: Falcons QB Michael Penix Jr. had a career-high three passing touchdowns in the team’s Week 9 loss; Penix has yet to have back-to-back games with multiple passing touchdowns in his career. — ESPN Research
Bold prediction: The Colts will hold London under 50 receiving yards. The Colts have a wild split this season in which they rank first in DVOA (defense-adjusted value over average) against No. 1 receivers but 28th against No. 2s. They held Pittsburgh’s DK Metcalf to 6 yards last week! It’s schematic, not related to any specific cornerback, although it can’t hurt to have Gardner arriving this week. — Schatz
Fantasy nugget: The Colts’ offense will look to get back on track. Atlanta’s defense has allowed the sixth-fewest fantasy points per game to QBs, so expectations for the Indianapolis passing game should be modest. However, Taylor is positioned for a heavy workload behind a offensive line that ranks third in run block win rate (74.3%). The Falcons’ defense has also allowed the 10th-most rushing yards per game (124.4). See Week 10 rankings. — Moody
Betting nugget: The Colts are 5-0 outright and 4-1 against the spread (ATS) vs. teams with losing records this season. Read more. — ESPN Research
Maldonado’s pick: Colts 35, Falcons 10 Moody’s pick: Colts 24, Falcons 21 Schatz’s pick: Colts 28, Falcons 22 FPI prediction: IND, 69.6% (by an average of 7.7 points)
Matchup must-reads: How RBs Taylor, Robinson transcend their stats … Gardner cleared to debut for Colts … Falcons’ LG Bergeron is ‘week-to-week’
Stat to know: The Ravens have allowed only one passing touchdown over their past three games (tied for the fewest in the NFL over that span). — ESPN Research
Bold prediction: The Vikings will blitz less than usual. Minnesota’s defense blitzes 39% of the time, second in the league behind Atlanta, but Jackson is second with an 85.4 QBR against blitzes since the start of last season. Flores can switch things up to avoid Jackson’s strength. — Schatz
Fantasy nugget: Vikings kicker Will Reichard has scored 11 or more fantasy points in two of his past three games. The Ravens’ defense has improved significantly over their past three games in total yards allowed and points allowed, but it has still given up the second-most field goal attempts this season. As a result, Baltimore has allowed the seventh-most fantasy points per game to kickers. See Week 10 rankings. — Moody
Betting nugget: Jackson is 32-16-2 ATS in his career on the road (1-2 ATS this season). Read more. — ESPN Research
Maldonado’s pick: Ravens 27, Vikings 20 Moody’s pick: Ravens 31, Vikings 23 Schatz’s pick: Ravens 27, Vikings 20 FPI prediction: BAL, 62.5% (by an average of 4.8 points)
Matchup must-reads: How QB Jackson plans to succeed against Vikings’ pressure … QB McCarthy explains alter ego, viral glare
Stat to know: The Patriots have not allowed an opposing running back to reach 50 rushing yards; they are the only team to do so through the first nine games since 1950. — ESPN Research
Bold prediction: Bucs linebacker Yaya Diaby will have multiple sacks. Patriots left tackle Will Campbell is currently 56th among qualifying tackles with a pass block win rate of 83.8%, while taking sacks is Maye’s biggest weakness (34 in 2025). Only the Titans’ Cam Ward (38) has more. — Schatz
Fantasy nugget: Maye remains firmly on the QB1 radar, even against a tough Bucs defense that has allowed just 16.6 fantasy points per game to QBs. However, Tampa Bay has also given up the fifth-most rushing yards per game to the position, which boosts Maye’s upside. It’s still difficult to trust any of the Patriots’ pass catchers in fantasy lineups, as Maye has spread targets evenly across the group. See Week 10 rankings. — Moody
Betting nugget: Bucs QB Baker Mayfield is 20-31-1 ATS as a favorite in his career (10-8 ATS with Bucs). Read more. — ESPN Research
Maldonado’s pick: Patriots 30, Buccaneers 17 Moody’s pick: Patriots 30, Buccaneers 28 Schatz’s pick: Buccaneers 23, Patriots 21 FPI prediction: TB, 57.5% (by an average of 2.7 points)
Stat to know: Tagovailoa’s 11 interceptions so far are tied for the most in the NFL with the Raiders’ Geno Smith. With another pick, Tagovailoa would be first Dolphins QB since Chad Henne in 2010 (12) with 12 or more interceptions in his first 10 games of a season. — ESPN Research
Bold prediction: The Bills will keep running back De’von Achane from picking up long gains in the passing game. Buffalo is second in DVOA against running backs as receivers, and it kept Achane to just 29 yards on seven catches when these teams met in Week 3. — Schatz
Fantasy nugget: Bills tight end Dalton Kincaid has averaged 16.0 fantasy points in the four games this season in which he has seen at least six targets. Even though he splits snaps with two other TEs (Dawson Knox and Jackson Hawes), Kincaid leads the group in routes run, which is what matters most for fantasy production. He’s in an excellent spot against a defense that allows the fifth-most fantasy points per game to TEs. See Week 10 rankings. — Moody
Betting nugget: The Bills are 1-4 ATS in their past five games as favorites. Read more. — ESPN Research
Maldonado’s pick: Bills 27, Dolphins 10 Moody’s pick: Bills 38, Dolphins 17 Schatz’s pick: Bills 27, Dolphins 16 FPI prediction: BUF, 69.6 (by an average of 7.5 points)
Matchup must-reads: Bills tried — and failed — to make a move at the deadline … Why Dolphins kept Waddle, Chubb at trade deadline
Stat to know: The Jaguars are one of three teams with a negative points differential but a winning record (Panthers and Bears). — ESPN Research
Bold prediction: Texans TE Dalton Schultz will record his first receiving touchdown of the season. Jacksonville is 25th in DVOA against tight ends and allows an opponent-adjusted 78 yards per game to the position, 31st in the league. Plus, backup QBs tend to love their tight end security blankets. — Schatz
Fantasy nugget: Quarterbacks have averaged the fewest fantasy points per game against Houston (11.5), and receivers have averaged the second fewest (26.0). Houston is one of the rare defenses that fantasy managers can comfortably hold for the entire season. On the other side of the matchup, managers looking for a TE streamer should consider Schultz, as the Jaguars allow the second-most fantasy points per game to the position. See Week 10 rankings. — Moody